Grapes Help Protect Against Organ Damage Caused By Metabolic Syndrome

Grapes Help Protect Against Organ Damage Caused By Metabolic Syndrome

Natural components in grapes, called polyphenols, have been found to have properties that can help protect organ damage caused by metabolic syndrome. The research, presented at the Experimental Biology conference in Boston, reveals even more health benefits of consuming grapes.


Metabolic syndrome is a major public health concern in the U.S., it is characterized as being a group of conditions including:

  • High blood sugar level
  • Increased blood pressure
  • Increased blood triglycerides-which increases heart attack and stroke risk
  • Low levels of HDL cholesterol-the good cholesterol
  • Excess body fat around the waist

The lead author of the study, E. Mitchell Seymour, Ph.D., led research that observed the health effects that a high fat, American-style diet with added grapes and without grapes had on the liver, heart, kidneys, and fat tissue in obesity-prone rats. The grapes were a mix of green, red, and black and were part of the animals diet for a total duration of 90 days.

At the end of the 90-day period, the researchers noted that the rats on the added grape diet had reduced inflammatory markers in their body, in particular in the abdominal fat tissue and liver. In addition, they found that those on the grape-enriched diet had lower kidney, liver and abdominal fat weight than those who didn’t eat grapes.

grapes 2

The team also found that grape intake increased markers of antioxidant defense, particularly in the liver and kidneys. Intake of fruits and vegetables is thought to reduce these risks, and grapes have shown benefits in multiple studies.

Previous research, conducted by scientists at the University of Michigan Health System, similarly found that eating grapes has been shown to reduce risk factors related to cardiovascular disease and metabolic syndrome. “Our study suggests that a grape-enriched diet may play a critical role in protecting against metabolic syndrome and the toll it takes on the body and its organs. Both inflammation and oxidative stress play a role in cardiovascular disease progression and organ dysfunction in Type 2 diabetes. Grape intake impacted both of these components in several tissues which is a very promising finding.”


From the June 2013 Wellstyles Monthly Newsletter from the Valley Schools Employee Benefits Trust (VSEBT) courtesy of Rebecca McGonigle


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